- Psycho (franchise), an American horror thriller film franchise based on the Bloch novel
- Psycho (1960 film), a film by Alfred Hitchcock
- Psycho II, (1983) a sequel to the original film, following the plot of the previous novel
- Psycho III, (1986) a follow-up to the 2nd film.
- Psycho IV: The Beginning, a 1990 sequel to the 1986 film, made for cable television.
- Psycho (1998 film), a remake of the original film by Gus Van Sant starring Vince Vaughn.
- Psycho (2008 film), an Indian film (in Kannada language) directed by Devadatta
- Psycho (2013 film), a Telugu film directed by Kishore Bhargava